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Platelet-activating factor receptor (PAFR)

Organism	Human 1 1. [409] Poisson, C, Rollin S, Veronneau S, Bousquet SM, Larrivee JF, Le Gouill C, Boulay G, Stankova J, Rola-Pleszczynski M. 2009. Caveolae facilitate but are not essential for platelet-activating factor-mediated calcium mobilization and extracellular signal-regulated kinase activation. J Immunol. 183:2747-57.
Functional implication	MβCD treatment reduced PAF-induced IP production, ca2+ mobilization and ERK phosphorylation 1 1. a. b. [409] Poisson, C, Rollin S, Veronneau S, Bousquet SM, Larrivee JF, Le Gouill C, Boulay G, Stankova J, Rola-Pleszczynski M. 2009. Caveolae facilitate but are not essential for platelet-activating factor-mediated calcium mobilization and extracellular signal-regulated kinase activation. J Immunol. 183:2747-57.
Methods used to detect raft association	Detergent-free 1 1. a. b. c. [409] Poisson, C, Rollin S, Veronneau S, Bousquet SM, Larrivee JF, Le Gouill C, Boulay G, Stankova J, Rola-Pleszczynski M. 2009. Caveolae facilitate but are not essential for platelet-activating factor-mediated calcium mobilization and extracellular signal-regulated kinase activation. J Immunol. 183:2747-57.
Mechanism of raft association	Putative palmitoylation site 1 1. a. b. c. d. [409] Poisson, C, Rollin S, Veronneau S, Bousquet SM, Larrivee JF, Le Gouill C, Boulay G, Stankova J, Rola-Pleszczynski M. 2009. Caveolae facilitate but are not essential for platelet-activating factor-mediated calcium mobilization and extracellular signal-regulated kinase activation. J Immunol. 183:2747-57.
Caveolin-binding motif	Yes 1 1. a. b. c. d. e. [409] Poisson, C, Rollin S, Veronneau S, Bousquet SM, Larrivee JF, Le Gouill C, Boulay G, Stankova J, Rola-Pleszczynski M. 2009. Caveolae facilitate but are not essential for platelet-activating factor-mediated calcium mobilization and extracellular signal-regulated kinase activation. J Immunol. 183:2747-57.
Cell type	CHO cells 1; HEK-293 1 1. a. b. c. d. e. f. g. [409] Poisson, C, Rollin S, Veronneau S, Bousquet SM, Larrivee JF, Le Gouill C, Boulay G, Stankova J, Rola-Pleszczynski M. 2009. Caveolae facilitate but are not essential for platelet-activating factor-mediated calcium mobilization and extracellular signal-regulated kinase activation. J Immunol. 183:2747-57.
Species	Hamster 1; Human 1 1. a. b. c. d. e. f. g. h. i. [409] Poisson, C, Rollin S, Veronneau S, Bousquet SM, Larrivee JF, Le Gouill C, Boulay G, Stankova J, Rola-Pleszczynski M. 2009. Caveolae facilitate but are not essential for platelet-activating factor-mediated calcium mobilization and extracellular signal-regulated kinase activation. J Immunol. 183:2747-57.
Receptor expression	Stable expression 1; Transient expression 1 1. a. b. c. d. e. f. g. h. i. j. k. [409] Poisson, C, Rollin S, Veronneau S, Bousquet SM, Larrivee JF, Le Gouill C, Boulay G, Stankova J, Rola-Pleszczynski M. 2009. Caveolae facilitate but are not essential for platelet-activating factor-mediated calcium mobilization and extracellular signal-regulated kinase activation. J Immunol. 183:2747-57.

Refrences

Hamster 1; Human 1

1. a. b. c. d. e. f. g. h. i. [409] Poisson, C, Rollin S, Veronneau S, Bousquet SM, Larrivee JF, Le Gouill C, Boulay G, Stankova J, Rola-Pleszczynski M. 2009. Caveolae facilitate but are not essential for platelet-activating factor-mediated calcium mobilization and extracellular signal-regulated kinase activation. J Immunol. 183:2747-57.