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Lipoxin A4 receptor

Organism	Human 1 1. [466] Mitchell, D, O'Meara SJ, Gaffney A, Crean JKG, Kinsella TB, Godson C. 2007. The Lipoxin A4 receptor is coupled to SHP-2 activation: implications for regulation of receptor tyrosine kinases.. The Journal of biological chemistry. 282(21):15606-18.
Functional implication	MβCD treatment reduces LXA4-dependent Platelet-derived growth factor receptor β dephosphorylation 1; LXA4 binding to receptor promotes SHP-2 recruitment to lipid raft 1 1. a. b. c. [466] Mitchell, D, O'Meara SJ, Gaffney A, Crean JKG, Kinsella TB, Godson C. 2007. The Lipoxin A4 receptor is coupled to SHP-2 activation: implications for regulation of receptor tyrosine kinases.. The Journal of biological chemistry. 282(21):15606-18.
Methods used to detect raft association	Detergent-dependent 1 1. a. b. c. d. [466] Mitchell, D, O'Meara SJ, Gaffney A, Crean JKG, Kinsella TB, Godson C. 2007. The Lipoxin A4 receptor is coupled to SHP-2 activation: implications for regulation of receptor tyrosine kinases.. The Journal of biological chemistry. 282(21):15606-18.
Mechanism of raft association	n.a 1. a. b. c. d. [466] Mitchell, D, O'Meara SJ, Gaffney A, Crean JKG, Kinsella TB, Godson C. 2007. The Lipoxin A4 receptor is coupled to SHP-2 activation: implications for regulation of receptor tyrosine kinases.. The Journal of biological chemistry. 282(21):15606-18.
Caveolin-binding motif
Cell type	HEK-293 1 1. a. b. c. d. e. [466] Mitchell, D, O'Meara SJ, Gaffney A, Crean JKG, Kinsella TB, Godson C. 2007. The Lipoxin A4 receptor is coupled to SHP-2 activation: implications for regulation of receptor tyrosine kinases.. The Journal of biological chemistry. 282(21):15606-18.
Species	Human 1 1. a. b. c. d. e. f. [466] Mitchell, D, O'Meara SJ, Gaffney A, Crean JKG, Kinsella TB, Godson C. 2007. The Lipoxin A4 receptor is coupled to SHP-2 activation: implications for regulation of receptor tyrosine kinases.. The Journal of biological chemistry. 282(21):15606-18.
Receptor expression	Stable overexpression 1 1. a. b. c. d. e. f. g. [466] Mitchell, D, O'Meara SJ, Gaffney A, Crean JKG, Kinsella TB, Godson C. 2007. The Lipoxin A4 receptor is coupled to SHP-2 activation: implications for regulation of receptor tyrosine kinases.. The Journal of biological chemistry. 282(21):15606-18.

Refrences

Human 1

1. a. b. c. d. e. f. [466] Mitchell, D, O'Meara SJ, Gaffney A, Crean JKG, Kinsella TB, Godson C. 2007. The Lipoxin A4 receptor is coupled to SHP-2 activation: implications for regulation of receptor tyrosine kinases.. The Journal of biological chemistry. 282(21):15606-18.