GABA-B receptor

Organism	Rat 1; Hamster 2 1. [344] Becher, A, White JH, McIlhinney RA. 2001. The gamma-aminobutyric acid receptor B, but not the metabotropic glutamate receptor type-1, associates with lipid rafts in the rat cerebellum. J Neurochem. 79:787-95. 2. [342] Becher, A, Green A, Ige AO, Wise A, White JH, McIlhinney RA. 2004. Ectopically expressed gamma-aminobutyric acid receptor B is functionally down-regulated in isolated lipid raft-enriched membranes. Biochem Biophys Res Commun. 321:981-7.
Functional implication	Receptor localization in lipid raft may inhibit signaling 2 1. [344] Becher, A, White JH, McIlhinney RA. 2001. The gamma-aminobutyric acid receptor B, but not the metabotropic glutamate receptor type-1, associates with lipid rafts in the rat cerebellum. J Neurochem. 79:787-95. 2. a. b. [342] Becher, A, Green A, Ige AO, Wise A, White JH, McIlhinney RA. 2004. Ectopically expressed gamma-aminobutyric acid receptor B is functionally down-regulated in isolated lipid raft-enriched membranes. Biochem Biophys Res Commun. 321:981-7.
Methods used to detect raft association	Detergent-dependent 1, 2 1. a. b. [344] Becher, A, White JH, McIlhinney RA. 2001. The gamma-aminobutyric acid receptor B, but not the metabotropic glutamate receptor type-1, associates with lipid rafts in the rat cerebellum. J Neurochem. 79:787-95. 2. a. b. c. [342] Becher, A, Green A, Ige AO, Wise A, White JH, McIlhinney RA. 2004. Ectopically expressed gamma-aminobutyric acid receptor B is functionally down-regulated in isolated lipid raft-enriched membranes. Biochem Biophys Res Commun. 321:981-7.
Mechanism of raft association	n.a 1. a. b. [344] Becher, A, White JH, McIlhinney RA. 2001. The gamma-aminobutyric acid receptor B, but not the metabotropic glutamate receptor type-1, associates with lipid rafts in the rat cerebellum. J Neurochem. 79:787-95. 2. a. b. c. [342] Becher, A, Green A, Ige AO, Wise A, White JH, McIlhinney RA. 2004. Ectopically expressed gamma-aminobutyric acid receptor B is functionally down-regulated in isolated lipid raft-enriched membranes. Biochem Biophys Res Commun. 321:981-7.
Caveolin-binding motif
Cell type	Cerebellum 1; CHO cells 2 1. a. b. c. [344] Becher, A, White JH, McIlhinney RA. 2001. The gamma-aminobutyric acid receptor B, but not the metabotropic glutamate receptor type-1, associates with lipid rafts in the rat cerebellum. J Neurochem. 79:787-95. 2. a. b. c. d. [342] Becher, A, Green A, Ige AO, Wise A, White JH, McIlhinney RA. 2004. Ectopically expressed gamma-aminobutyric acid receptor B is functionally down-regulated in isolated lipid raft-enriched membranes. Biochem Biophys Res Commun. 321:981-7.
Species	Rat 1; Hamster 2 1. a. b. c. d. [344] Becher, A, White JH, McIlhinney RA. 2001. The gamma-aminobutyric acid receptor B, but not the metabotropic glutamate receptor type-1, associates with lipid rafts in the rat cerebellum. J Neurochem. 79:787-95. 2. a. b. c. d. e. [342] Becher, A, Green A, Ige AO, Wise A, White JH, McIlhinney RA. 2004. Ectopically expressed gamma-aminobutyric acid receptor B is functionally down-regulated in isolated lipid raft-enriched membranes. Biochem Biophys Res Commun. 321:981-7.
Receptor expression	Endogenous 1; Stable transfection 2 1. a. b. c. d. e. [344] Becher, A, White JH, McIlhinney RA. 2001. The gamma-aminobutyric acid receptor B, but not the metabotropic glutamate receptor type-1, associates with lipid rafts in the rat cerebellum. J Neurochem. 79:787-95. 2. a. b. c. d. e. f. [342] Becher, A, Green A, Ige AO, Wise A, White JH, McIlhinney RA. 2004. Ectopically expressed gamma-aminobutyric acid receptor B is functionally down-regulated in isolated lipid raft-enriched membranes. Biochem Biophys Res Commun. 321:981-7.

Refrences

Rat 1; Hamster 2

1. a. b. c. d. [344] Becher, A, White JH, McIlhinney RA. 2001. The gamma-aminobutyric acid receptor B, but not the metabotropic glutamate receptor type-1, associates with lipid rafts in the rat cerebellum. J Neurochem. 79:787-95.
2. a. b. c. d. e. [342] Becher, A, Green A, Ige AO, Wise A, White JH, McIlhinney RA. 2004. Ectopically expressed gamma-aminobutyric acid receptor B is functionally down-regulated in isolated lipid raft-enriched membranes. Biochem Biophys Res Commun. 321:981-7.

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GABA-B receptor