Adenosine A1 receptor

Organism

Rat 1, Pig 2, Syrian hamster 3

Functional implication

Agonist stimulation leads to translocation out of 1or into caveolae and caveolae-dependent internalization 2,3

Methods used to detect raft association

Detergent-free 1, 2 Electron microscopy 3; Confocal microscopy 3

Mechanism of raft association

Bound caveolin-3  1 and caveolin-13

Caveolin-binding motif

Yes 2

Cell type

Ventricular cardiomyocyte 1; Kidney epithelial cell 2 Smooth muscle cell line 3

Species

Rat 1; Pig 2; Syrian hamster 3

Receptor expression

Endogenous 1, 2, 3

Refrences